4M4D

Crystal structure of lipopolysaccharide binding protein

Summary for 4M4D

• Entry DOI: 10.2210/pdb4m4d/pdb
• Descriptor: Lipopolysaccharide-binding protein, 2-acetamido-2-deoxy-beta-D-glucopyranose, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE (3 entities in total)
• Functional Keywords: beta barrel, immune response, lipopolysaccharide, blood, lipid binding protein
• Biological source: Mus musculus (mouse)
• Total number of polymer chains: 2
• Total formula weight: 107405.58

Authors

Eckert, J.K.,Kim, Y.J.,Kim, J.I.,Gurtler, K.,Oh, D.Y.,Ploeg, A.H.,Pickkers, P.,Lundvall, L.,Hamann, L.,Giamarellos-Bourboulis, E.,Kubarenko, A.V.,Weber, A.N.,Kabesch, M.,Kumpf, O.,An, H.J.,Lee, J.O.,Schumann, R.R. (deposition date: 2013-08-07, release date: 2013-10-30, Last modification date: 2023-11-08)

• Primary citation: Eckert, J.K.,Kim, Y.J.,Kim, J.I.,Gurtler, K.,Oh, D.Y.,Sur, S.,Lundvall, L.,Hamann, L.,van der Ploeg, A.,Pickkers, P.,Giamarellos-Bourboulis, E.,Kubarenko, A.V.,Weber, A.N.,Kabesch, M.,Kumpf, O.,An, H.J.,Lee, J.O.,Schumann, R.R.; The crystal structure of lipopolysaccharide binding protein reveals the location of a frequent mutation that impairs innate immunity.; Immunity, 39:647-660, 2013; PubMed: 24120359; DOI: 10.1016/j.immuni.2013.09.005

Experimental method

X-RAY DIFFRACTION (2.909 Å)