4M4D

Crystal structure of lipopolysaccharide binding protein

4M4D の概要

• エントリーDOI: 10.2210/pdb4m4d/pdb
• 分子名称: Lipopolysaccharide-binding protein, 2-acetamido-2-deoxy-beta-D-glucopyranose, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE (3 entities in total)
• 機能のキーワード: beta barrel, immune response, lipopolysaccharide, blood, lipid binding protein
• 由来する生物種: Mus musculus (mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 107405.58

構造登録者

Eckert, J.K.,Kim, Y.J.,Kim, J.I.,Gurtler, K.,Oh, D.Y.,Ploeg, A.H.,Pickkers, P.,Lundvall, L.,Hamann, L.,Giamarellos-Bourboulis, E.,Kubarenko, A.V.,Weber, A.N.,Kabesch, M.,Kumpf, O.,An, H.J.,Lee, J.O.,Schumann, R.R. (登録日: 2013-08-07, 公開日: 2013-10-30, 最終更新日: 2023-11-08)

• 主引用文献: Eckert, J.K.,Kim, Y.J.,Kim, J.I.,Gurtler, K.,Oh, D.Y.,Sur, S.,Lundvall, L.,Hamann, L.,van der Ploeg, A.,Pickkers, P.,Giamarellos-Bourboulis, E.,Kubarenko, A.V.,Weber, A.N.,Kabesch, M.,Kumpf, O.,An, H.J.,Lee, J.O.,Schumann, R.R.; The crystal structure of lipopolysaccharide binding protein reveals the location of a frequent mutation that impairs innate immunity.; Immunity, 39:647-660, 2013; PubMed: 24120359; DOI: 10.1016/j.immuni.2013.09.005

実験手法

X-RAY DIFFRACTION (2.909 Å)