4M47
structure of human DNA polymerase complexed with 8-BrG in the template base paired with incoming non-hydrolyzable GTP
Summary for 4M47
| Entry DOI | 10.2210/pdb4m47/pdb |
| Related | 1BPX 3ISB 4M2Y |
| Descriptor | DNA polymerase beta, a synthetic template, a synthetic upstream primer, ... (8 entities in total) |
| Functional Keywords | dna synthesis, base excision repair, transferase-dna complex, transferase/dna |
| Biological source | Homo sapiens (human) More |
| Cellular location | Nucleus: P06746 |
| Total number of polymer chains | 4 |
| Total formula weight | 47111.73 |
| Authors | Koag, M.C.,Min, K.,Monzingo, A.F.,Lee, S. (deposition date: 2013-08-06, release date: 2014-01-22, Last modification date: 2024-02-28) |
| Primary citation | Koag, M.C.,Min, K.,Lee, S. Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289:6289-6298, 2014 Cited by PubMed: 24425881DOI: 10.1074/jbc.M113.537803 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.37 Å) |
Structure validation
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