4M2Y
Structure of human DNA polymerase beta complexed with 8-BrG as the template base in a 1-nucleotide gapped DNA
Summary for 4M2Y
Entry DOI | 10.2210/pdb4m2y/pdb |
Related | 1BPX 3ISB 4M47 |
Descriptor | DNA polymerase beta, template DNA strand, up-primer, ... (6 entities in total) |
Functional Keywords | promutagenic 8-halogenated g insertion, polymerase -dna complex, base excision repair, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P06746 |
Total number of polymer chains | 4 |
Total formula weight | 46671.39 |
Authors | Koag, M.C.,Min, K.,Monzingo, A.F.,Lee, S. (deposition date: 2013-08-05, release date: 2014-01-22, Last modification date: 2023-09-20) |
Primary citation | Koag, M.C.,Min, K.,Lee, S. Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289:6289-6298, 2014 Cited by PubMed: 24425881DOI: 10.1074/jbc.M113.537803 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.27 Å) |
Structure validation
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