4M2M

Crystal structure of PLP-dependent cyclase OrfR in complex with PLP-L-Arg

Summary for 4M2M

Entry DOI	10.2210/pdb4m2m/pdb
Related	4M23 4M25 4M26 4M27 4M2C 4M2E 4M2F 4M2G 4M2I 4M2J 4M2K
Descriptor	Aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ARGININE, ... (4 entities in total)
Functional Keywords	cyclase, plp binding, transferase
Biological source	Streptomyces lavendulae
Total number of polymer chains	1
Total formula weight	44142.64
Authors	Chang, C.Y.,Liu, Y.C.,Lyu, S.Y.,Wu, C.C.,Li, T.L. (deposition date: 2013-08-05, release date: 2014-06-18, Last modification date: 2023-11-08)
Primary citation	Chang, C.Y.,Lyu, S.Y.,Liu, Y.C.,Hsu, N.S.,Wu, C.C.,Tang, C.F.,Lin, K.H.,Ho, J.Y.,Wu, C.J.,Tsai, M.D.,Li, T.L. Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms. Angew.Chem.Int.Ed.Engl., 53:1943-1948, 2014 Cited by PubMed: 24505011 DOI: 10.1002/anie.201307989 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.58 Å)

Structure validation