4LVX

Structure of the THF riboswitch bound to tetrahydrobiopterin

4LVX の概要

• エントリーDOI: 10.2210/pdb4lvx/pdb
• 関連するPDBエントリー: 3SD3 4LVV 4LVW 4LVY 4LVZ 4LW0
• 分子名称: THF riboswitch, 5,6,7,8-TETRAHYDROBIOPTERIN (3 entities in total)
• 機能のキーワード: aptamers, nucleotide, bacillus subtilis, bacterial proteins, base sequence, binding sites, calorimetry, folic acid, gene expression regulation, bacterial, guanine, leucovorin, ligands, magnesium, molecular sequence data, nucleic acid conformation, point mutation, protein binding, protein structure, secondary, rna, riboswitch, s-adenosylmethionine, streptococcus mutans, terminator regions, genetic, tetrahydrofolates, thermodynamics, transcription, three-way junction, pseudoknot, regulation, ncrna, tetrahydrobiopterin binding, mrna
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29331.64

構造登録者

Trausch, J.J.,Batey, R.T. (登録日: 2013-07-26, 公開日: 2014-03-19, 最終更新日: 2024-02-28)

• 主引用文献: Trausch, J.J.,Batey, R.T.; A Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate Riboswitch.; Chem.Biol., 21:205-216, 2014; PubMed: 24388757; DOI: 10.1016/j.chembiol.2013.11.012

実験手法

X-RAY DIFFRACTION (1.9 Å)