4LUN

Structure of the N-terminal mIF4G domain from S. cerevisiae Upf2, a protein involved in the degradation of mRNAs containing premature stop codons

4LUN の概要

• エントリーDOI: 10.2210/pdb4lun/pdb
• 分子名称: Nonsense-mediated mRNA decay protein 2, CHLORIDE ION (3 entities in total)
• 機能のキーワード: heat-repeat, mrna decay, rna binding protein
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast)
• 細胞内の位置: Cytoplasm : P38798
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36673.59

構造登録者

Fourati, Z.,Roy, B.,Millan, C.,Courreux, P.D.,Kervestin, S.,van Tilbeurgh, H.,He, F.,Uson, I.,Jacobson, A.,Graille, M. (登録日: 2013-07-25, 公開日: 2014-07-30, 最終更新日: 2024-02-28)

• 主引用文献: Fourati, Z.,Roy, B.,Millan, C.,Coureux, P.D.,Kervestin, S.,van Tilbeurgh, H.,He, F.,Uson, I.,Jacobson, A.,Graille, M.; A highly conserved region essential for NMD in the Upf2 N-terminal domain.; J.Mol.Biol., 426:3689-3702, 2014; PubMed: 25277656; DOI: 10.1016/j.jmb.2014.09.015

実験手法

X-RAY DIFFRACTION (1.641 Å)