4LSZ
Caspase-7 in Complex with DARPin D7.18
Summary for 4LSZ
Entry DOI | 10.2210/pdb4lsz/pdb |
Related | 2P2C 3IBC |
Descriptor | Caspase-7 subunit p20, Caspase-7 subunit p10, DARPin D7.18, ... (4 entities in total) |
Functional Keywords | complex structure, caspase-7, selected and specific darpin d7.18, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P55210 P55210 |
Total number of polymer chains | 6 |
Total formula weight | 100942.07 |
Authors | Fluetsch, A.,Lukarska, M.,Gruetter, M.G. (deposition date: 2013-07-23, release date: 2014-07-02, Last modification date: 2023-09-20) |
Primary citation | Flutsch, A.,Ackermann, R.,Schroeder, T.,Lukarska, M.,Hausammann, G.J.,Weinert, C.,Briand, C.,Grutter, M.G. Combined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demise. Biochem.J., 461:279-290, 2014 Cited by PubMed: 24779913DOI: 10.1042/BJ20131456 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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