4LRT

Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site

Summary for 4LRT

• Entry DOI: 10.2210/pdb4lrt/pdb
• Related: 4LRS
• Descriptor: 4-hydroxy-2-oxovalerate aldolase, Acetaldehyde dehydrogenase, PYRUVIC ACID, ... (9 entities in total)
• Functional Keywords: rosmmann fold, tim barrel, dehydrogenase, aldolase, lyase-oxidoreductase complex, lyase/oxidoreductase
• Biological source: Thermomonospora curvata; More
• Total number of polymer chains: 4
• Total formula weight: 145229.53

Authors

Fischer, B.,Branlant, G.,Talfournier, F.,Gruez, A. (deposition date: 2013-07-20, release date: 2013-09-04, Last modification date: 2024-11-06)

• Primary citation: Fischer, B.,Branlant, G.,Talfournier, F.,Gruez, A.; Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site; To be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)