4LRT

Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site

4LRT の概要

• エントリーDOI: 10.2210/pdb4lrt/pdb
• 関連するPDBエントリー: 4LRS
• 分子名称: 4-hydroxy-2-oxovalerate aldolase, Acetaldehyde dehydrogenase, PYRUVIC ACID, ... (9 entities in total)
• 機能のキーワード: rosmmann fold, tim barrel, dehydrogenase, aldolase, lyase-oxidoreductase complex, lyase/oxidoreductase
• 由来する生物種: Thermomonospora curvata; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 145229.53

構造登録者

Fischer, B.,Branlant, G.,Talfournier, F.,Gruez, A. (登録日: 2013-07-20, 公開日: 2013-09-04, 最終更新日: 2024-11-06)

• 主引用文献: Fischer, B.,Branlant, G.,Talfournier, F.,Gruez, A.; Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site; To be Published,

実験手法

X-RAY DIFFRACTION (1.5 Å)