4LQF

Structure of murine IgG2b A2C7-Fab in complex with vaccinia antigen A33R at the resolution of 2.3 Angstroms

Summary for 4LQF

• Entry DOI: 10.2210/pdb4lqf/pdb
• Related: 4LU5 4M1G
• Descriptor: A33R, Murine IgG2b A2C7 Heavy chain Fab domain, Murine IgG2b A2C7 Light chain Fab domain, ... (5 entities in total)
• Functional Keywords: igg domain, antibody-antigen complex, fv, ch1, igg2b, antigen-binding fragment (fab), a33r antigen, papain digest of the mab, eev membrane (outer membrane of vaccinia ev form), immune system
• Biological source: Vaccinia virus; More
• Total number of polymer chains: 3
• Total formula weight: 58683.36

Authors

Matho, M.H.,Schlossman, A.M.,Zajonc, D.M. (deposition date: 2013-07-17, release date: 2014-08-06, Last modification date: 2023-09-20)

• Primary citation: Matho, M.H.,Schlossman, A.,Meng, X.,Benhnia, M.R.,Kaever, T.,Buller, M.,Doronin, K.,Parker, S.,Peters, B.,Crotty, S.,Xiang, Y.,Zajonc, D.M.; Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer.; Plos Pathog., 11:e1005148-e1005148, 2015; PubMed: 26325270; DOI: 10.1371/journal.ppat.1005148

Experimental method

X-RAY DIFFRACTION (2.3 Å)