4LOR

C1s CUB1-EGF-CUB2 in complex with a collagen-like peptide from C1q

4LOR の概要

• エントリーDOI: 10.2210/pdb4lor/pdb
• 分子名称: Complement C1s subcomponent heavy chain, collagen-like peptide from C1q, CALCIUM ION, ... (6 entities in total)
• 機能のキーワード: cub domain, egf-like domain, protein collagen complex, c1 complex, hydrolase-protein binding complex, hydrolase/protein binding
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 38942.01

構造登録者

Wallis, R.,Venkatraman Girija, U.,Moody, P.C.E.,Marshall, J.E. (登録日: 2013-07-13, 公開日: 2013-08-07, 最終更新日: 2020-07-29)

• 主引用文献: Venkatraman Girija, U.,Gingras, A.R.,Marshall, J.E.,Panchal, R.,Sheikh, M.A.,Gal, P.,Schwaeble, W.J.,Mitchell, D.A.,Moody, P.C.,Wallis, R.; Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation.; Proc.Natl.Acad.Sci.USA, 110:13916-13920, 2013; PubMed: 23922389; DOI: 10.1073/pnas.1311113110

実験手法

X-RAY DIFFRACTION (2.5 Å)