4LNI

B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of the transition state complex

4LNI の概要

• エントリーDOI: 10.2210/pdb4lni/pdb
• 関連するPDBエントリー: 4LNF 4LNK 4LNN 4LNO
• 分子名称: Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: alpha-beta, tnra, glnra, ligase
• 由来する生物種: Bacillus subtilis
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 611606.72

構造登録者

Schumacher, M.A.,Chinnam, N.,Tonthat, N.,Fisher, S.,Wray, L. (登録日: 2013-07-11, 公開日: 2013-11-06, 最終更新日: 2024-02-28)

• 主引用文献: Murray, D.S.,Chinnam, N.,Tonthat, N.K.,Whitfill, T.,Wray, L.V.,Fisher, S.H.,Schumacher, M.A.; Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism.; J.Biol.Chem., 288:35801-35811, 2013; PubMed: 24158439; DOI: 10.1074/jbc.M113.519496

実験手法

X-RAY DIFFRACTION (2.5793 Å)