4LH2

Structure of mouse 1-Pyrroline-5-Carboxylate Dehydrogenase (ALDH4A1) complexed with succinate

Summary for 4LH2

Entry DOI	10.2210/pdb4lh2/pdb
Related	3V9G 3V9H 3V9I 3V9J 3V9K 3V9L 4LGZ 4LH0 4LH1 4LH3
Descriptor	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, PENTAETHYLENE GLYCOL, SUCCINIC ACID, ... (4 entities in total)
Functional Keywords	proline catabolism, substrate recognition, rossmann fold, oxidoreductase
Biological source	Mus musculus (mouse)
Cellular location	Mitochondrion matrix (By similarity): Q8CHT0
Total number of polymer chains	2
Total formula weight	124621.16
Authors	Pemberton, T.A.,Tanner, J.J. (deposition date: 2013-06-30, release date: 2013-08-28, Last modification date: 2023-09-20)
Primary citation	Pemberton, T.A.,Tanner, J.J. Structural basis of substrate selectivity of Delta (1)-pyrroline-5-carboxylate dehydrogenase (ALDH4A1): Semialdehyde chain length. Arch.Biochem.Biophys., 538:34-40, 2013 Cited by PubMed: 23928095 DOI: 10.1016/j.abb.2013.07.024 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.673 Å)

Structure validation