4LFT

Structure of alpha-elapitoxin-Dpp2d isolated from Black Mamba (Dendroaspis polylepis) venom

4LFT の概要

• エントリーDOI: 10.2210/pdb4lft/pdb
• 分子名称: Alpha-elapitoxin-Dpp2a (2 entities in total)
• 機能のキーワード: long neurotoxin, three-finger-toxin, disulfide-rich, acetylcholine receptor inhibitor activity, expressed by the venom gland, toxin
• 由来する生物種: Dendroaspis polylepis polylepis (Black mamba)
• 細胞内の位置: Secreted : P01396
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 16026.63

構造登録者

Wang, C.I.A.,Reeks, T.,Lewis, R.J.,Alewood, P.F.,Durek, T. (登録日: 2013-06-27, 公開日: 2014-06-11, 最終更新日: 2023-09-20)

• 主引用文献: Wang, C.I.,Reeks, T.,Vetter, I.,Vergara, I.,Kovtun, O.,Lewis, R.J.,Alewood, P.F.,Durek, T.; Isolation and Structural and Pharmacological Characterization of alpha-Elapitoxin-Dpp2d, an Amidated Three Finger Toxin from Black Mamba Venom.; Biochemistry, 53:3758-3766, 2014; PubMed: 24867092; DOI: 10.1021/bi5004475

実験手法

X-RAY DIFFRACTION (1.7 Å)