4LCD

Structure of an Rsp5xUbxSna3 complex: Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3

4LCD の概要

• エントリーDOI: 10.2210/pdb4lcd/pdb
• 分子名称: E3 ubiquitin-protein ligase RSP5, Protein SNA3, Ubiquitin (3 entities in total)
• 機能のキーワード: ligase, e3, rsp5, nedd4, ubiquitin, hect, sna3, thioester, maleimide, crosslink, ligase-protein binding complex, ligase/protein binding
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast); 詳細
• 細胞内の位置: Cytoplasm: P39940; Membrane; Multi-pass membrane protein: P14359; Ubiquitin: Cytoplasm (By similarity): P0CG48
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 125228.63

構造登録者

Kamadurai, H.B.,Miller, D.,Schulman, B.A. (登録日: 2013-06-21, 公開日: 2013-08-14, 最終更新日: 2024-02-28)

• 主引用文献: Kamadurai, H.B.,Qiu, Y.,Deng, A.,Harrison, J.S.,Macdonald, C.,Actis, M.,Rodrigues, P.,Miller, D.J.,Souphron, J.,Lewis, S.M.,Kurinov, I.,Fujii, N.,Hammel, M.,Piper, R.,Kuhlman, B.,Schulman, B.A.; Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3.; Elife, 2:e00828-e00828, 2013; PubMed: 23936628; DOI: 10.7554/eLife.00828

実験手法

X-RAY DIFFRACTION (3.1 Å)