4LAY
Crystal Structure Analysis of FKBP52, Complex with I63
Summary for 4LAY
Entry DOI | 10.2210/pdb4lay/pdb |
Related | 1Q1C 4LAV 4LAW 4LAX |
Descriptor | Peptidyl-prolyl cis-trans isomerase FKBP4, {3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid (3 entities in total) |
Functional Keywords | fk-506 binding domain, hsp90 cochaperone, immunophilin, peptidyl-prolyl isomerase, protein folding, isomerase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytosol (By similarity): Q02790 |
Total number of polymer chains | 1 |
Total formula weight | 31949.09 |
Authors | Bracher, A.,Kozany, C.,Haehle, A.,Wild, P.,Zacharias, M.,Hausch, F. (deposition date: 2013-06-20, release date: 2013-08-21, Last modification date: 2023-09-20) |
Primary citation | Bracher, A.,Kozany, C.,Hahle, A.,Wild, P.,Zacharias, M.,Hausch, F. Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge. J.Mol.Biol., 425:4134-4144, 2013 Cited by PubMed: 23933011DOI: 10.1016/j.jmb.2013.07.041 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report