4LAC
Crystal Structure of Protein Phosphatase 2A (PP2A) and PP2A phosphatase activator (PTPA) complex with ATPgammaS
Summary for 4LAC
Entry DOI | 10.2210/pdb4lac/pdb |
Descriptor | Serine/threonine-protein phosphatase 2A activator, PP2A Scaffold Subunit A, Truncated, an internal deletion of PP2A A, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ... (8 entities in total) |
Functional Keywords | pp2a, ptpa, protein phosphatase, signaling pathway regulation, chaperone, hydrolase-signaling protein complex, hydrolase/signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q15257 P67775 |
Total number of polymer chains | 3 |
Total formula weight | 100398.89 |
Authors | Guo, F.,Stanevich, V.,Wlodarchak, N.,Satyshur, K.A.,Xing, Y. (deposition date: 2013-06-19, release date: 2013-10-09, Last modification date: 2023-09-20) |
Primary citation | Guo, F.,Stanevich, V.,Wlodarchak, N.,Sengupta, R.,Jiang, L.,Satyshur, K.A.,Xing, Y. Structural basis of PP2A activation by PTPA, an ATP-dependent activation chaperone. Cell Res., 24:190-203, 2014 Cited by PubMed: 24100351DOI: 10.1038/cr.2013.138 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.82 Å) |
Structure validation
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