4LAC

Crystal Structure of Protein Phosphatase 2A (PP2A) and PP2A phosphatase activator (PTPA) complex with ATPgammaS

4LAC の概要

• エントリーDOI: 10.2210/pdb4lac/pdb
• 分子名称: Serine/threonine-protein phosphatase 2A activator, PP2A Scaffold Subunit A, Truncated, an internal deletion of PP2A A, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ... (8 entities in total)
• 機能のキーワード: pp2a, ptpa, protein phosphatase, signaling pathway regulation, chaperone, hydrolase-signaling protein complex, hydrolase/signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: Q15257 P67775
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 100398.89

構造登録者

Guo, F.,Stanevich, V.,Wlodarchak, N.,Satyshur, K.A.,Xing, Y. (登録日: 2013-06-19, 公開日: 2013-10-09, 最終更新日: 2023-09-20)

• 主引用文献: Guo, F.,Stanevich, V.,Wlodarchak, N.,Sengupta, R.,Jiang, L.,Satyshur, K.A.,Xing, Y.; Structural basis of PP2A activation by PTPA, an ATP-dependent activation chaperone.; Cell Res., 24:190-203, 2014; PubMed: 24100351; DOI: 10.1038/cr.2013.138

実験手法

X-RAY DIFFRACTION (2.82 Å)