Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4L96

Structure of the complex between the F360L PPARgamma mutant and the ligand LT175 (space group I222)

Summary for 4L96
Entry DOI10.2210/pdb4l96/pdb
Related3B3K 4L98
DescriptorPeroxisome proliferator-activated receptor gamma, (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid (3 entities in total)
Functional Keywordstranscription factor, rxralpha, transcription-transcription inhibitor complex, transcription/transcription inhibitor
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight31694.84
Authors
Pochetti, G.,Montanari, R.,Capelli, D.,Chiaraluce, R.,Consalvi, V.,Pasquo, A.,Lori, C.,Laghezza, A.,Loiodice, F. (deposition date: 2013-06-18, release date: 2014-06-25, Last modification date: 2023-09-20)
Primary citationLori, C.,Pasquo, A.,Montanari, R.,Capelli, D.,Consalvi, V.,Chiaraluce, R.,Cervoni, L.,Loiodice, F.,Laghezza, A.,Aschi, M.,Giorgi, A.,Pochetti, G.
Structural basis of the transactivation deficiency of the human PPAR gamma F360L mutant associated with familial partial lipodystrophy.
Acta Crystallogr.,Sect.D, 70:1965-1976, 2014
Cited by
PubMed: 25004973
DOI: 10.1107/S1399004714009638
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.38 Å)
Structure validation

217705

건을2024-03-27부터공개중

PDB statisticsPDBj update infoContact PDBjnumon