4L6R
Structure of the class B human glucagon G protein coupled receptor
Summary for 4L6R
Entry DOI | 10.2210/pdb4l6r/pdb |
Descriptor | Soluble cytochrome b562 and Glucagon receptor chimera, DI(HYDROXYETHYL)ETHER (2 entities in total) |
Functional Keywords | human glucagon receptor, diabetes, gpcr network, psi-biology, membrane protein, novel protein engineering, structural genomics, protein structure initiative, gpcr, membrane |
Biological source | Escherichia coli (human) More |
Cellular location | Cell membrane ; Multi-pass membrane protein : P47871 |
Total number of polymer chains | 1 |
Total formula weight | 48256.96 |
Authors | Siu, F.Y.,He, M.,de Graaf, C.,Han, G.W.,Yang, D.,Zhang, Z.,Zhou, C.,Xu, Q.,Wacker, D.,Joseph, J.S.,Liu, W.,Lau, J.,Cherezov, V.,Katritch, V.,Wang, M.W.,Stevens, R.C.,GPCR Network (GPCR) (deposition date: 2013-06-12, release date: 2013-07-24, Last modification date: 2023-09-20) |
Primary citation | Siu, F.Y.,He, M.,de Graaf, C.,Han, G.W.,Yang, D.,Zhang, Z.,Zhou, C.,Xu, Q.,Wacker, D.,Joseph, J.S.,Liu, W.,Lau, J.,Cherezov, V.,Katritch, V.,Wang, M.W.,Stevens, R.C. Structure of the human glucagon class B G-protein-coupled receptor. Nature, 499:444-449, 2013 Cited by PubMed: 23863937DOI: 10.1038/nature12393 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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