4L6R

Structure of the class B human glucagon G protein coupled receptor

Summary for 4L6R

• Entry DOI: 10.2210/pdb4l6r/pdb
• Descriptor: Soluble cytochrome b562 and Glucagon receptor chimera, DI(HYDROXYETHYL)ETHER (2 entities in total)
• Functional Keywords: human glucagon receptor, diabetes, gpcr network, psi-biology, membrane protein, novel protein engineering, structural genomics, protein structure initiative, gpcr, membrane
• Biological source: Escherichia coli (human); More
• Cellular location: Cell membrane ; Multi-pass membrane protein : P47871
• Total number of polymer chains: 1
• Total formula weight: 48256.96

Authors

Siu, F.Y.,He, M.,de Graaf, C.,Han, G.W.,Yang, D.,Zhang, Z.,Zhou, C.,Xu, Q.,Wacker, D.,Joseph, J.S.,Liu, W.,Lau, J.,Cherezov, V.,Katritch, V.,Wang, M.W.,Stevens, R.C.,GPCR Network (GPCR) (deposition date: 2013-06-12, release date: 2013-07-24, Last modification date: 2023-09-20)

• Primary citation: Siu, F.Y.,He, M.,de Graaf, C.,Han, G.W.,Yang, D.,Zhang, Z.,Zhou, C.,Xu, Q.,Wacker, D.,Joseph, J.S.,Liu, W.,Lau, J.,Cherezov, V.,Katritch, V.,Wang, M.W.,Stevens, R.C.; Structure of the human glucagon class B G-protein-coupled receptor.; Nature, 499:444-449, 2013; PubMed: 23863937; DOI: 10.1038/nature12393

Experimental method

X-RAY DIFFRACTION (3.3 Å)