4L5C

Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with adenine in space group P212121

Summary for 4L5C

• Entry DOI: 10.2210/pdb4l5c/pdb
• Related: 4L5A
• Descriptor: S-methyl-5'-thioadenosine phosphorylase, ADENINE, GLYCEROL, ... (4 entities in total)
• Functional Keywords: transferase, phsophorylase, nucleoside phosphorylase, enzyme
• Biological source: Schistosoma mansoni (Blood fluke)
• Cellular location: Cytoplasm : I0B503
• Total number of polymer chains: 6
• Total formula weight: 212920.21

Authors

Torini, J.R.,DeMarco, R.,Brandao-Neto, J.,Pereira, H.M. (deposition date: 2013-06-10, release date: 2014-06-11, Last modification date: 2023-09-20)

• Primary citation: Torini, J.R.,Brandao-Neto, J.,DeMarco, R.,Pereira, H.D.; Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway.; Plos Negl Trop Dis, 10:e0005178-e0005178, 2016; PubMed: 27935959; DOI: 10.1371/journal.pntd.0005178

Experimental method

X-RAY DIFFRACTION (2.075 Å)