4L5A

Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with tubercidin

Summary for 4L5A

Entry DOI	10.2210/pdb4l5a/pdb
Descriptor	S-methyl-5'-thioadenosine phosphorylase, '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, SULFATE ION, ... (4 entities in total)
Functional Keywords	transferase, phosphorylase, nucleoside phosphorylase, enzyme, transferase-antibiotic complex, transferase/antibiotic
Biological source	Schistosoma mansoni (Blood fluke)
Cellular location	Cytoplasm : I0B503
Total number of polymer chains	6
Total formula weight	213730.78
Authors	Torini, J.R.,DeMarco, R.,Brandao-Neto, J.,Pereira, H.M. (deposition date: 2013-06-10, release date: 2014-06-11, Last modification date: 2024-02-28)
Primary citation	Torini, J.R.,Brandao-Neto, J.,DeMarco, R.,Pereira, H.D. Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway. Plos Negl Trop Dis, 10:e0005178-e0005178, 2016 Cited by PubMed: 27935959 DOI: 10.1371/journal.pntd.0005178 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2993 Å)

Structure validation