4L57
High resolutin structure of human cytosolic 5'(3')-deoxyribonucleotidase
Summary for 4L57
Entry DOI | 10.2210/pdb4l57/pdb |
Descriptor | 5'(3')-deoxyribonucleotidase, cytosolic type, MAGNESIUM ION, PHOSPHATE ION, ... (6 entities in total) |
Functional Keywords | 5'-nucleotidase, protein conformation, sequence homology, had-like, hydrolase, dephosphorylation |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q8TCD5 |
Total number of polymer chains | 2 |
Total formula weight | 46424.43 |
Authors | Pachl, P.,Brynda, J.,Rezacova, P. (deposition date: 2013-06-10, release date: 2014-02-12, Last modification date: 2024-02-28) |
Primary citation | Pachl, P.,Fabry, M.,Rosenberg, I.,Simak, O.,Rezacova, P.,Brynda, J. Structures of human cytosolic and mitochondrial nucleotidases: implications for structure-based design of selective inhibitors. Acta Crystallogr. D Biol. Crystallogr., 70:461-470, 2014 Cited by PubMed: 24531480DOI: 10.1107/S1399004713030502 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.08 Å) |
Structure validation
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