4L3B

X-ray structure of the HRV2 A particle uncoating intermediate

Summary for 4L3B

• Entry DOI: 10.2210/pdb4l3b/pdb
• Related: 1FPN 3TN9
• Descriptor: Protein VP1, Protein VP2, Protein VP3 (3 entities in total)
• Functional Keywords: hrv2 capsid, virus
• Biological source: Human rhinovirus A2 (HRV-2); More
• Cellular location: Capsid protein VP0: Virion . Capsid protein VP4: Virion . Capsid protein VP2: Virion . Capsid protein VP3: Virion . Capsid protein VP1: Virion . Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3AB: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Viral protein genome-linked: Virion . Protease 3C: Host cytoplasm . Protein 3CD: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . RNA-directed RNA polymerase: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : P04936 P04936 P04936
• Total number of polymer chains: 3
• Total formula weight: 88042.18

Authors

Vives-Adrian, L.,Querol-Audi, J.,Garriga, D.,Pous, J.,Verdaguer, N. (deposition date: 2013-06-05, release date: 2013-11-27, Last modification date: 2023-09-20)

• Primary citation: Pickl-Herk, A.,Luque, D.,Vives-Adrian, L.,Querol-Audi, J.,Garriga, D.,Trus, B.L.,Verdaguer, N.,Blaas, D.,Caston, J.R.; Uncoating of common cold virus is preceded by RNA switching as determined by X-ray and cryo-EM analyses of the subviral A-particle.; Proc.Natl.Acad.Sci.USA, 110:20063-20068, 2013; PubMed: 24277846; DOI: 10.1073/pnas.1312128110

Experimental method

X-RAY DIFFRACTION (6.5 Å)