4KYS

Clostridium botulinum thiaminase I in complex with thiamin

4KYS の概要

• エントリーDOI: 10.2210/pdb4kys/pdb
• 分子名称: Thiamine pyridinylase I, 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, CITRIC ACID, ... (5 entities in total)
• 機能のキーワード: periplasmic binding protein type 2 fold, thiaminase i, thiamin degradation, transferase
• 由来する生物種: Clostridium botulinum
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 99031.76

構造登録者

Sikowitz, M.D.,Shome, B.,Zhang, Y.,Begley, T.P.,Ealick, S.E. (登録日: 2013-05-29, 公開日: 2013-10-30, 最終更新日: 2024-02-28)

• 主引用文献: Sikowitz, M.D.,Shome, B.,Zhang, Y.,Begley, T.P.,Ealick, S.E.; Structure of a Clostridium botulinum C143S Thiaminase I/Thiamin Complex Reveals Active Site Architecture.; Biochemistry, 52:7830-7839, 2013; PubMed: 24079939; DOI: 10.1021/bi400841g

実験手法

X-RAY DIFFRACTION (2.18 Å)