4KYI
Crystal structure of the phospholipase VipD from Legionella pneumophila in complex with the human GTPase Rab5
Summary for 4KYI
Entry DOI | 10.2210/pdb4kyi/pdb |
Descriptor | VipD, Ras-related protein Rab-5C, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | phospholipase, protein binding-transport protein complex, protein binding/transport protein |
Biological source | Legionella pneumophila subsp. pneumophila More |
Cellular location | Cell membrane ; Lipid-anchor ; Cytoplasmic side : P51148 |
Total number of polymer chains | 8 |
Total formula weight | 322919.41 |
Authors | Lucas, M.,Gaspar, A.H.,Pallara, C.,Rojas, A.L.,Fernandez-Recio, J.,Machner, M.P.,Hierro, A. (deposition date: 2013-05-29, release date: 2014-08-13, Last modification date: 2015-07-29) |
Primary citation | Lucas, M.,Gaspar, A.H.,Pallara, C.,Rojas, A.L.,Fernandez-Recio, J.,Machner, M.P.,Hierro, A. Structural basis for the recruitment and activation of the Legionella phospholipase VipD by the host GTPase Rab5. Proc.Natl.Acad.Sci.USA, 111:E3514-E3523, 2014 Cited by PubMed: 25114243DOI: 10.1073/pnas.1405391111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.075 Å) |
Structure validation
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