4KXX

Human transketolase in covalent complex with donor ketose D-sedoheptulose-7-phosphate

4KXX の概要

• エントリーDOI: 10.2210/pdb4kxx/pdb
• 分子名称: Transketolase, (2R,3R,4S,5R,6S)-2,3,4,5,6,7-hexahydroxyheptyl dihydrogen phosphate, THIAMINE DIPHOSPHATE, ... (7 entities in total)
• 機能のキーワード: thiamin diphosphate, enzyme catalysis, pentose phosphate pathway, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 71157.06

構造登録者

Neumann, P.,Luedtke, S.,Ficner, R.,Tittmann, K. (登録日: 2013-05-28, 公開日: 2013-08-21, 最終更新日: 2023-09-20)

• 主引用文献: Ludtke, S.,Neumann, P.,Erixon, K.M.,Leeper, F.,Kluger, R.,Ficner, R.,Tittmann, K.; Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate.; Nat Chem, 5:762-767, 2013; PubMed: 23965678; DOI: 10.1038/nchem.1728

実験手法

X-RAY DIFFRACTION (1.03 Å)