4KWW

The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid

4KWW の概要

• エントリーDOI: 10.2210/pdb4kww/pdb
• 関連するPDBエントリー: 4KWV
• 分子名称: Nicotinate-nucleotide pyrophosphorylase [carboxylating], PHTHALIC ACID (3 entities in total)
• 機能のキーワード: nad, metabolism, type ii phosphoribosyltransferase, quinolinic acid, prpp, brain, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 188039.74

構造登録者

Malik, S.S.,Dimeka, P.N.,Ncube, Z.,Toth, E.A. (登録日: 2013-05-24, 公開日: 2013-10-02, 最終更新日: 2023-09-20)

• 主引用文献: Malik, S.S.,Patterson, D.N.,Ncube, Z.,Toth, E.A.; The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid.; Proteins, 82:405-414, 2014; PubMed: 24038671; DOI: 10.1002/prot.24406

実験手法