4KW6
Crystal structure of Peroxiredoxin-1 (C-terminal truncation mutant) from the human hookworm Ancylostoma ceylanicum bound to conoidin A
Summary for 4KW6
Entry DOI | 10.2210/pdb4kw6/pdb |
Related | 4FH8 |
Descriptor | Peroxiredoxin-1, 2,3-bis(bromomethyl)quinoxaline 1,4-dioxide (3 entities in total) |
Functional Keywords | 2-cys peroxiredoxin, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Ancylostoma ceylanicum |
Total number of polymer chains | 5 |
Total formula weight | 101851.93 |
Authors | Nguyen, J.B.,Modis, Y. (deposition date: 2013-05-23, release date: 2013-07-31, Last modification date: 2023-09-20) |
Primary citation | Nguyen, J.B.,Pool, C.D.,Wong, C.Y.,Treger, R.S.,Williams, D.L.,Cappello, M.,Lea, W.A.,Simeonov, A.,Vermeire, J.J.,Modis, Y. Peroxiredoxin-1 from the Human Hookworm Ancylostoma ceylanicum Forms a Stable Oxidized Decamer and Is Covalently Inhibited by Conoidin A. Chem.Biol., 20:991-1001, 2013 Cited by PubMed: 23891152DOI: 10.1016/j.chembiol.2013.06.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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