4KTL
Crystal structure of Mycobacterium tuberculosis CYP121 in complex with 4,4'-(3-((4-hydroxyphenyl)amino)-1H-pyrazole-4,5-diyl)diphenol
Summary for 4KTL
| Entry DOI | 10.2210/pdb4ktl/pdb |
| Related | 4KTF 4KTJ 4KTK |
| Descriptor | Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... (5 entities in total) |
| Functional Keywords | p450, oxidoreductase, cyy, c-c bond formation, assumed cytosol |
| Biological source | Mycobacterium tuberculosis |
| Total number of polymer chains | 1 |
| Total formula weight | 44630.85 |
| Authors | Hudson, S.A. (deposition date: 2013-05-20, release date: 2013-07-03, Last modification date: 2023-09-20) |
| Primary citation | Hudson, S.A.,Surade, S.,Coyne, A.G.,McLean, K.J.,Leys, D.,Munro, A.W.,Abell, C. Overcoming the Limitations of Fragment Merging: Rescuing a Strained Merged Fragment Series Targeting Mycobacterium tuberculosis CYP121. Chemmedchem, 8:1451-1456, 2013 Cited by PubMed: 23788280DOI: 10.1002/cmdc.201300219 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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