4KT8
The complex structure of Rv3378c-Y51FY90F with substrate, TPP
Summary for 4KT8
Entry DOI | 10.2210/pdb4kt8/pdb |
Related | 3VX5 3VX9 3VXA 3W3I |
Descriptor | Diterpene synthase, PHOSPHATE ION, (2E)-3-methyl-5-[(1R,2S,8aS)-1,2,5,5-tetramethyl-1,2,3,5,6,7,8,8a-octahydronaphthalen-1-yl]pent-2-en-1-yl trihydrogen diphosphate, ... (4 entities in total) |
Functional Keywords | diterpene synthase, hydrolase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 34774.84 |
Authors | Chan, H.C.,Feng, X.,Ko, T.P.,Huang, C.H.,Hu, Y.,Zheng, Y.,Bogue, S.,Nakano, C.,Hoshino, T.,Zhang, L.,Lv, P.,Liu, W.,Crick, D.C.,Liang, P.H.,Wang, A.H.,Oldfield, E.,Guo, R.T. (deposition date: 2013-05-20, release date: 2014-02-26, Last modification date: 2023-11-08) |
Primary citation | Chan, H.C.,Feng, X.,Ko, T.P.,Huang, C.H.,Hu, Y.,Zheng, Y.,Bogue, S.,Nakano, C.,Hoshino, T.,Zhang, L.,Lv, P.,Liu, W.,Crick, D.C.,Liang, P.H.,Wang, A.H.,Oldfield, E.,Guo, R.T. Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. J.Am.Chem.Soc., 136:2892-2896, 2014 Cited by PubMed: 24475925DOI: 10.1021/ja413127v PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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