4KS8
PAK6 kinase domain in complex with sunitinib
Summary for 4KS8
Entry DOI | 10.2210/pdb4ks8/pdb |
Related | 4KS7 |
Descriptor | Serine/threonine-protein kinase PAK 6, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide (3 entities in total) |
Functional Keywords | protein kinase, phosphotransfer, phosphorylation, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9NQU5 |
Total number of polymer chains | 1 |
Total formula weight | 33700.03 |
Authors | Gao, J.,Boggon, T.J. (deposition date: 2013-05-17, release date: 2013-09-11, Last modification date: 2024-10-09) |
Primary citation | Gao, J.,Ha, B.H.,Lou, H.J.,Morse, E.M.,Zhang, R.,Calderwood, D.A.,Turk, B.E.,Boggon, T.J. Substrate and Inhibitor Specificity of the Type II p21-Activated Kinase, PAK6. Plos One, 8:e77818-e77818, 2013 Cited by PubMed: 24204982DOI: 10.1371/journal.pone.0077818 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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