4KQE

The mutant structure of the human glycyl-tRNA synthetase E71G

Summary for 4KQE

• Entry DOI: 10.2210/pdb4kqe/pdb
• Related: 4KR2 4KR3
• Descriptor: Glycine--tRNA ligase, GLYCEROL (3 entities in total)
• Functional Keywords: rossmann fold, aminoacylation, trna-gly, ligase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : P41250
• Total number of polymer chains: 1
• Total formula weight: 78724.86

Authors

Qin, X.,Hao, Z.,Tian, Q.,Zhang, Z.,Zhou, C.,Xie, W. (deposition date: 2013-05-15, release date: 2014-05-21, Last modification date: 2023-11-08)

• Primary citation: Deng, X.,Qin, X.,Chen, L.,Jia, Q.,Zhang, Y.,Zhang, Z.,Lei, D.,Ren, G.,Zhou, Z.,Wang, Z.,Li, Q.,Xie, W.; Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) during Catalysis; J.Biol.Chem., 291:5740-5752, 2016; PubMed: 26797133; DOI: 10.1074/jbc.M115.679126

Experimental method

X-RAY DIFFRACTION (2.739 Å)