4KH6

Toxoplasma gondii NTPDase1 C258S/C268S E493G crystallized with Mg and AMPNP

Summary for 4KH6

• Entry DOI: 10.2210/pdb4kh6/pdb
• Related: 4A57 4A59 4A5A 4A5B 4JEP 4KH4 4KH5
• Descriptor: Nucleoside-triphosphatase 2, 5'-O-[(R)-hydroxy(phosphonoamino)phosphoryl]adenosine, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: hydrolase, actin-like fold, ntpdase
• Biological source: Toxoplasma gondii
• Cellular location: Secreted: Q27895
• Total number of polymer chains: 2
• Total formula weight: 136845.07

Authors

Krug, U.,Totzauer, R.,Strater, N. (deposition date: 2013-04-30, release date: 2013-11-06, Last modification date: 2017-11-15)

• Primary citation: Krug, U.,Totzauer, R.,Zebisch, M.,Strater, N.; The ATP/ADP substrate specificity switch between Toxoplasma gondii NTPDase1 and NTPDase3 is caused by an altered mode of binding of the substrate base.; Chembiochem, 14:2292-2300, 2013; PubMed: 24115522; DOI: 10.1002/cbic.201300441

Experimental method

X-RAY DIFFRACTION (2.4 Å)