4K8R

An Antibody Against the C-terminal Domain of PCSK9 lowers LDL Cholesterol Levels in vivo

Summary for 4K8R

• Entry DOI: 10.2210/pdb4k8r/pdb
• Related: 4LKC
• Descriptor: Proprotein convertase subtilisin/kexin type 9, Fab1, light chain, Fab1, heavy chain, ... (7 entities in total)
• Functional Keywords: immunoglobulin, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 165247.47

Authors

Schiele, F.,Nar, H. (deposition date: 2013-04-18, release date: 2013-05-08, Last modification date: 2019-08-21)

• Primary citation: Schiele, F.,Park, J.,Redemann, N.,Luippold, G.,Nar, H.; An Antibody against the C-Terminal Domain of PCSK9 Lowers LDL Cholesterol Levels In Vivo.; J.Mol.Biol., 426:843-852, 2014; PubMed: 24252255; DOI: 10.1016/j.jmb.2013.11.011

Experimental method

X-RAY DIFFRACTION (3.22 Å)