4K7P
Generation and Characterization of a Unique Reagent that Recognizes a Panel of Recombinant Human Monoclonal Antibody Therapeutics in the Presence of Endogenous Human IgG
Summary for 4K7P
Entry DOI | 10.2210/pdb4k7p/pdb |
Descriptor | antibody rhumAb6 Fab fragment light chain, antibody rhumAb6 Fab fragment heavy chain, antibody 10C4 Fab fragment heavy chain, ... (4 entities in total) |
Functional Keywords | immunoglobulin, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 4 |
Total formula weight | 95651.62 |
Authors | Eigenbrot, C.,Shia, S. (deposition date: 2013-04-17, release date: 2013-08-07, Last modification date: 2023-09-20) |
Primary citation | Wang, X.,Quarmby, V.,Ng, C.,Chuntharapai, A.,Shek, T.,Eigenbrot, C.,Kelley, R.F.,Shia, S.,McCutcheon, K.,Lowe, J.,Leddy, C.,Coachman, K.,Cain, G.,Chu, F.,Hotzel, I.,Maia, M.,Wakshull, E.,Yang, J. Generation and characterization of a unique reagent that recognizes a panel of recombinant human monoclonal antibody therapeutics in the presence of endogenous human IgG. MAbs, 5:540-554, 2013 Cited by PubMed: 23774668DOI: 10.4161/mabs.24822 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
Download full validation report