4K7F
Newly identified epitope V60 from HBV core protein complexed with HLA-A*0201
Summary for 4K7F
Entry DOI | 10.2210/pdb4k7f/pdb |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Core protein, ... (4 entities in total) |
Functional Keywords | host-virus interaction, immune response, disease mutation, viral replication, ig-like domain, immune system, tcr, membrane glycoprotein, viral capsid protein |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769 |
Total number of polymer chains | 6 |
Total formula weight | 89595.67 |
Authors | Meng, S.D.,Zhang, Y.,Wu, Y.,Qi, J.X. (deposition date: 2013-04-17, release date: 2013-06-05, Last modification date: 2022-08-24) |
Primary citation | Zhang, Y.,Ren, Y.,Wu, Y.,Zhao, B.,Qiu, L.,Li, X.,Xu, D.,Liu, J.,Gao, G.F.,Meng, S. The L60V variation in hepatitis B virus core protein elicits new epitope-specific cytotoxic T lymphocytes and enhances viral replication. J.Virol., 87:8075-8084, 2013 Cited by PubMed: 23678186DOI: 10.1128/JVI.00577-13 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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