4K7F

Newly identified epitope V60 from HBV core protein complexed with HLA-A*0201

4K7F の概要

• エントリーDOI: 10.2210/pdb4k7f/pdb
• 分子名称: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Core protein, ... (4 entities in total)
• 機能のキーワード: host-virus interaction, immune response, disease mutation, viral replication, ig-like domain, immune system, tcr, membrane glycoprotein, viral capsid protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 89595.67

構造登録者

Meng, S.D.,Zhang, Y.,Wu, Y.,Qi, J.X. (登録日: 2013-04-17, 公開日: 2013-06-05, 最終更新日: 2022-08-24)

• 主引用文献: Zhang, Y.,Ren, Y.,Wu, Y.,Zhao, B.,Qiu, L.,Li, X.,Xu, D.,Liu, J.,Gao, G.F.,Meng, S.; The L60V variation in hepatitis B virus core protein elicits new epitope-specific cytotoxic T lymphocytes and enhances viral replication.; J.Virol., 87:8075-8084, 2013; PubMed: 23678186; DOI: 10.1128/JVI.00577-13

実験手法

X-RAY DIFFRACTION (2 Å)