4K5B

Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W

Summary for 4K5B

Entry DOI	10.2210/pdb4k5b/pdb
Related	4K5A
Descriptor	Apoptosis regulator BCL-W, Bcl-2-like protein 2 (3 entities in total)
Functional Keywords	apoptosis, anti-apoptotic bcl-2 family, bcl-w;crystal structure, ligand binding-competent conformation, darpins
Biological source	Escherichia coli More
Cellular location	Mitochondrion membrane; Peripheral membrane protein (By similarity): 4K5B
Total number of polymer chains	4
Total formula weight	76808.17
Authors	Schilling, J.,Schoeppe, J.,Sauer, E.,Plueckthun, A. (deposition date: 2013-04-14, release date: 2014-04-16, Last modification date: 2024-03-20)
Primary citation	Schilling, J.,Schoppe, J.,Sauer, E.,Pluckthun, A. Co-Crystallization with Conformation-Specific Designed Ankyrin Repeat Proteins Explains the Conformational Flexibility of BCL-W J.Mol.Biol., 426:2346-2362, 2014 Cited by PubMed: 24747052 DOI: 10.1016/j.jmb.2014.04.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation