4K5A

Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W

Summary for 4K5A

• Entry DOI: 10.2210/pdb4k5a/pdb
• Related: 4K5B
• Descriptor: Bcl-2-like protein 2, Designed Ankyrin Repeat Protein 013_D12 (3 entities in total)
• Functional Keywords: apoptosis, anti-apoptotic bcl-2 family, bcl-w;crystal structure, ligand binding-competent conformation, darpins
• Biological source: Bos taurus (bovine,cow,domestic cattle,domestic cow); More
• Cellular location: Mitochondrion membrane; Peripheral membrane protein (By similarity): Q1RMX3
• Total number of polymer chains: 2
• Total formula weight: 38381.93

Authors

Schilling, J.,Schoeppe, J.,Sauer, E.,Plueckthun, A. (deposition date: 2013-04-14, release date: 2014-04-16, Last modification date: 2024-03-20)

• Primary citation: Schilling, J.,Schoppe, J.,Sauer, E.,Pluckthun, A.; Co-Crystallization with Conformation-Specific Designed Ankyrin Repeat Proteins Explains the Conformational Flexibility of BCL-W; J.Mol.Biol., 426:2346-2362, 2014; PubMed: 24747052; DOI: 10.1016/j.jmb.2014.04.010

Experimental method