4K5A
Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W
Summary for 4K5A
Entry DOI | 10.2210/pdb4k5a/pdb |
Related | 4K5B |
Descriptor | Bcl-2-like protein 2, Designed Ankyrin Repeat Protein 013_D12 (3 entities in total) |
Functional Keywords | apoptosis, anti-apoptotic bcl-2 family, bcl-w;crystal structure, ligand binding-competent conformation, darpins |
Biological source | Bos taurus (bovine,cow,domestic cattle,domestic cow) More |
Cellular location | Mitochondrion membrane; Peripheral membrane protein (By similarity): Q1RMX3 |
Total number of polymer chains | 2 |
Total formula weight | 38381.93 |
Authors | Schilling, J.,Schoeppe, J.,Sauer, E.,Plueckthun, A. (deposition date: 2013-04-14, release date: 2014-04-16, Last modification date: 2024-03-20) |
Primary citation | Schilling, J.,Schoppe, J.,Sauer, E.,Pluckthun, A. Co-Crystallization with Conformation-Specific Designed Ankyrin Repeat Proteins Explains the Conformational Flexibility of BCL-W J.Mol.Biol., 426:2346-2362, 2014 Cited by PubMed: 24747052DOI: 10.1016/j.jmb.2014.04.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
Download full validation report