4K5A

Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W

4K5A の概要

• エントリーDOI: 10.2210/pdb4k5a/pdb
• 関連するPDBエントリー: 4K5B
• 分子名称: Bcl-2-like protein 2, Designed Ankyrin Repeat Protein 013_D12 (3 entities in total)
• 機能のキーワード: apoptosis, anti-apoptotic bcl-2 family, bcl-w;crystal structure, ligand binding-competent conformation, darpins
• 由来する生物種: Bos taurus (bovine,cow,domestic cattle,domestic cow); 詳細
• 細胞内の位置: Mitochondrion membrane; Peripheral membrane protein (By similarity): Q1RMX3
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 38381.93

構造登録者

Schilling, J.,Schoeppe, J.,Sauer, E.,Plueckthun, A. (登録日: 2013-04-14, 公開日: 2014-04-16, 最終更新日: 2024-03-20)

• 主引用文献: Schilling, J.,Schoppe, J.,Sauer, E.,Pluckthun, A.; Co-Crystallization with Conformation-Specific Designed Ankyrin Repeat Proteins Explains the Conformational Flexibility of BCL-W; J.Mol.Biol., 426:2346-2362, 2014; PubMed: 24747052; DOI: 10.1016/j.jmb.2014.04.010

実験手法

X-RAY DIFFRACTION (1.5 Å)