4K3H

Immunoglobulin lambda variable domain L5(L89S) fluorogen activationg protein in complex with malachite green

Summary for 4K3H

• Entry DOI: 10.2210/pdb4k3h/pdb
• Related: 4K3G
• Descriptor: Immunoglobulin lambda variable domain L5(L89S), 4-{bis[4-(dimethylamino)phenyl]methyl}phenol, GLYCEROL, ... (5 entities in total)
• Functional Keywords: immunoglobulin fold, fluorescensce, malachite green, o-mannosylation, thr27, immune system-inhibitor complex, immune system/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 8
• Total formula weight: 103293.38

Authors

Stanfield, R.L.,Szent-Gyorgyi, C.,Wilson, I.A. (deposition date: 2013-04-10, release date: 2013-10-09, Last modification date: 2020-07-29)

• Primary citation: Szent-Gyorgyi, C.,Stanfield, R.L.,Andreko, S.,Dempsey, A.,Ahmed, M.,Capek, S.,Waggoner, A.S.,Wilson, I.A.,Bruchez, M.P.; Malachite Green Mediates Homodimerization of Antibody VL Domains to Form a Fluorescent Ternary Complex with Singular Symmetric Interfaces.; J.Mol.Biol., 425:4595-4613, 2013; PubMed: 23978698; DOI: 10.1016/j.jmb.2013.08.014

Experimental method

X-RAY DIFFRACTION (2.45 Å)