4K1J

Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding

4K1J の概要

• エントリーDOI: 10.2210/pdb4k1j/pdb
• 関連するPDBエントリー: 4K1H 4K1I 4K1K
• 分子名称: Neuraminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: beta-propeller, glycoside hydrolase enzymes, hydrolase
• 由来する生物種: Influenza A virus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 88988.50

構造登録者

Wu, Y.,Gao, F.,Qi, J.X.,Gao, G.F. (登録日: 2013-04-05, 公開日: 2013-06-05, 最終更新日: 2020-07-29)

• 主引用文献: Wu, Y.,Qin, G.,Gao, F.,Liu, Y.,Vavricka, C.J.,Qi, J.,Jiang, H.,Yu, K.,Gao, G.F.; Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding; Sci Rep, 3:1551-1551, 2013; PubMed: 23531861; DOI: 10.1038/srep01551

実験手法

X-RAY DIFFRACTION (2.2 Å)