4K0A

Crystal structure of CD4-mimetic miniprotein M48U7 in complex with HIV-1 YU2 gp120

Summary for 4K0A

• Entry DOI: 10.2210/pdb4k0a/pdb
• Related: 4JZW 4JZZ 4K0A
• Related PRD ID: PRD_001099
• Descriptor: HIV-1 YU2 gp120 glycoprotein, CD4-MIMETIC MINIPROTEIN M48U7, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: hiv-1 attachment glycoprotein gp120, hiv-1 envelope, viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 2
• Total formula weight: 46941.32

Authors

Acharya, P.,Kwong, P.D. (deposition date: 2013-04-03, release date: 2013-06-12, Last modification date: 2020-07-29)

• Primary citation: Acharya, P.,Luongo, T.S.,Louder, M.K.,McKee, K.,Yang, Y.,Do Kwon, Y.,Mascola, J.R.,Kessler, P.,Martin, L.,Kwong, P.D.; Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 A Cocrystal Structure of gp120 and M48U1.; Structure, 21:1018-1029, 2013; PubMed: 23707685; DOI: 10.1016/j.str.2013.04.015

Experimental method

X-RAY DIFFRACTION (2.13 Å)