4JU0

Crystal structure of 2009 pandemic influenza virus hemagglutinin mutant D225E complexed with human receptor analogue LSTc

4JU0 の概要

• エントリーDOI: 10.2210/pdb4ju0/pdb
• 関連するPDBエントリー: 4JTV 4JTX 4JUG 4JUH 4JUJ
• 分子名称: Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: virus attachment, membrane fusion, viral protein
• 由来する生物種: Influenza A virus; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 333887.93

構造登録者

Zhang, W.,Shi, Y.,Qi, J.,Gao, F.,Li, Q.,Fan, Z.,Yan, J.,Gao, G.F. (登録日: 2013-03-24, 公開日: 2013-05-01, 最終更新日: 2023-11-08)

• 主引用文献: Zhang, W.,Shi, Y.,Qi, J.,Gao, F.,Li, Q.,Fan, Z.,Yan, J.,Gao, G.F.; Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution; J.Virol., 87:5949-5958, 2013; PubMed: 23514882; DOI: 10.1128/JVI.00545-13

実験手法

X-RAY DIFFRACTION (2.908 Å)