4JTU

Crystal structure of human dihydroorotate dehydrogenase (DHODH) with brequinar analogue

Summary for 4JTU

• Entry DOI: 10.2210/pdb4jtu/pdb
• Related: 4JS3 4JTS 4JTT
• Descriptor: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, OROTIC ACID, ... (7 entities in total)
• Functional Keywords: fmn binding, mitochondria inner membrane, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion inner membrane; Single-pass membrane protein: Q02127
• Total number of polymer chains: 1
• Total formula weight: 44150.71

Authors

Zhu, L.,Zhu, J.,Ren, X.,Li, H. (deposition date: 2013-03-24, release date: 2014-03-26, Last modification date: 2024-03-20)

• Primary citation: Zhu, L.,Li, H.,Zhu, J.,Ren, X.; Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057; To be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)