4JS2

Crystal structure of human Beta-galactoside alpha-2,6-sialyltransferase 1 in complex with CMP

4JS2 の概要

• エントリーDOI: 10.2210/pdb4js2/pdb
• 関連するPDBエントリー: 4JS1
• 分子名称: Beta-galactoside alpha-2,6-sialyltransferase 1, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CYTIDINE-5'-MONOPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: rossmann, gt-a, sialyltransferase, glycoprotein, sialylation, endoplasmatic reticulum, golgi, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 38932.73

構造登録者

Kuhn, B.,Benz, J.,Greif, M.,Engel, A.M.,Sobek, H.,Rudolph, M.G. (登録日: 2013-03-22, 公開日: 2013-07-31, 最終更新日: 2024-05-29)

• 主引用文献: Kuhn, B.,Benz, J.,Greif, M.,Engel, A.M.,Sobek, H.,Rudolph, M.G.; The structure of human alpha-2,6-sialyltransferase reveals the binding mode of complex glycans.; Acta Crystallogr.,Sect.D, 69:1826-1838, 2013; PubMed: 23999306; DOI: 10.1107/S0907444913015412

実験手法